In a new forum paper published in Trends in Biology, researchers from the University of North Carolina at Charlotte encapsulated the young field of nucleolar DNA damage response (DDR) pathways. The review highlights six mechanisms by which cells repair DNA damage, including one which was published five months ago in Nucleic Acids Research by the same authors. By attacking these mechanisms, future applied researchers will be able to trip up cancer’s reproduction and growth.
“The whole purpose of the Trends paper is to bring attention to scientists in the field and trigger their research,” said Charlotte Professor of Biological Sciences Shan Yan, the main author. “I did not realize the significance of this field, which is only fifteen years old, until a couple of years ago.”